Article
A cytoplasmic coiled-coil domain is required for histidine kinase activity of the yeast osmosensor, SLN1.
Molecular microbiology - 1 Jan 2002
Tao Wei, Malone Cheryl L, Ault Addison D, Deschenes Robert J, Fassler Jan S
Abstract excerpt
The yeast histidine kinase, Sln1p, is a plasma membrane-associated osmosensor that regulates the activity of the osmotic stress MAP kinase pathway. Changes in the osmotic environment of the cell influence the autokinase activity of the cytoplasmic kinase domain of Sln1p. Neither the nature of the...
Topics
- Amino Acid Sequence
- Binding Sites
- CCAAT-Enhancer-Binding Proteins
- Cytoplasm
- Fungal Proteins
- Intracellular Signaling Peptides and Proteins
- Leucine Zippers
- Molecular Sequence Data
- Mutagenesis
- Phenotype
- Protein Kinases
- Protein Structure, Tertiary
- Recombinant Fusion Proteins
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Structure-Activity Relationship