Article
A cytoplasmic coiled-coil domain is required for histidine kinase activity of the yeast osmosensor, SLN1.
Molecular microbiology - 1 Jan 2002
Tao Wei, Malone Cheryl L, Ault Addison D, Deschenes Robert J, Fassler Jan S
Abstract excerpt
The yeast histidine kinase, Sln1p, is a plasma membrane-associated osmosensor that regulates the activity of the osmotic stress MAP kinase pathway. Changes in the osmotic environment of the cell influence the autokinase activity of the cytoplasmic kinase domain of Sln1p. Neither the nature of the stimulus, the mechanism by which the osmotic signal is transduced nor the manner in which the kinase is regulated is...
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