Article
[Study of genotype frequencies of ANP 664G/A polymorphism in normal subjects and CVD patients, and its association with plasma ANP levels].
Rinsho byori. The Japanese journal of clinical pathology - 1 Mar 2002
Ohta Atsumi, Sonoda Akira, Yatabe Yoko, Takeshita Eiko, Saito Ikuo, Ito Daisuke, Tanahashi Norio, Fukuuchi Yasuo, Kikuchi Haruhito, Murata Mitsuru, Watanabe Kiyoaki
Abstract excerpt
Atrial natriuretic peptide (ANP) plays a crucial role in regulating body fluid volume and blood pressure, by promoting natriuresis and vasodilatation and by inhibiting the renin-angiotensin system. Plasma levels of ANP are elevated in heart failure and hypertension, and ANP is thus believed to be involved in the pathogenesis of cardiovascular disorders. Previous case-control studies have shown that a single...
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