Article
Damage control of DNA in nucleosome core particles: when a histone's loving, protective embrace is just not good enough.
Chemistry & biology - 1 Apr 2002
Turro Nicholas J
Abstract excerpt
Packaging DNA into nucleosome core particles generally offers protection from damage by molecules diffusing in solution. However, on page 403 of this issue, Barton and coworkers report that although noncovalently bound, activated Rh (Rhodium) does not readily bind within nucleosomal DNA, activated Rh that is covalently tethered to the 5' terminus of a histone-associated oligonucleotide oxidizes guanine bases from...
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