Article
The 807T allele in alpha2 integrin is protective against atherosclerotic arterial wall thickening and the occurrence of plaque in patients with type 2 diabetes.
Diabetes - 1 May 2002
Maeno Takaaki, Koyama Hidenori, Tahara Hideki, Komatsu Miyoko, Emoto Masanori, Shoji Tetsuo, Inaba Masaaki, Miki Takami, Okuno Yasuhisa, Nishizawa Yoshiki
Abstract excerpt
Polymorphism of alpha2 integrin (C807T) is shown to be associated with an increased incidence of thrombotic cardiovascular events. However, it is not clear whether this polymorphism is associated with atherosclerotic arterial wall thickening. In this study, we examined the association of C807T polymorphism with arterial wall thickness in 265 control subjects and 272 patients with type 2 diabetes. In all subjects,...
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