Article
Alpha 2 integrin +807 polymorphism in drug-induced gingival overgrowth.
Journal of dental research - 1 Dec 2005
Ogino M, Kido J, Bando M, Hayashi N, Wada C, Nagata T, Nishimura F, Soga Y, Takashiba S, Kubota T, Itagaki M, Shimada Y, Tai H, Yoshie H, Yamazaki N, Shinohara Y, Kataoka M
Abstract excerpt
Alpha2 integrin on fibroblasts is reported to play an important role in the induction of drug-induced gingival overgrowth, which is characterized by excessive accumulation of type I collagen in gingival connective tissue. Silent polymorphism 807 T/C within the alpha2 integrin gene is associated w...
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