Article
DSF nuclear receptor acts as a repressor in culture and in vivo.
Developmental biology - 15 May 2002
Pitman Jeffrey L, Tsai Chih-Cheng, Edeen Philip T, Finley Kim D, Evans Ronald M, McKeown Michael
Abstract excerpt
Loss-of-function mutations affecting the dissatisfaction (DSF) nuclear receptor alter both sexual behavior and the sex-specific nervous system in Drosophila. As a step toward understanding the way DSF controls development and function of the nervous system, we have analyzed the regulatory activities of the DSF protein. DSF prefers an atypical DNA half site, AAGTCA. Wild-type DSF, but not the point mutant DSF(7),...
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