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Article

REG1 binds to protein phosphatase type 1 and regulates glucose repression in Saccharomyces cerevisiae.

The EMBO journal - 1 Dec 1995

Tu J, Carlson M

Abstract excerpt

Protein phosphatase type 1 (PP1) is encoded by GLC7, an essential gene in Saccharomyces cerevisiae. The GLC7 phosphatase is required for glucose repression and appears to function antagonistically to the SNF1 protein kinase. Previously, we characterized a mutation, glc7-T152K, that relieves glucose repression but does not interfere with the function of GLC7 in glycogen metabolism. We proposed that the mutant...

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Identifiers

PMID: 8846786
DOI: 10.1002/j.1460-2075.1995.tb00282.x
PMCID: PMC394713

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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REG1 binds to protein phosphatase type 1 and regulates glucose repression in Saccharomyces cerevisiae.PMID 8846786Read ↗

The REG2 gene of Saccharomyces cerevisiae encodes a type 1 protein phosphatase-binding protein that functions with Reg1p and the Snf1 protein kinase to regulate growth.Semantic proximity Read ↗

Genetic interactions between REG1/HEX2 and GLC7, the gene encoding the protein phosphatase type 1 catalytic subunit in Saccharomyces cerevisiae.Semantic proximity Read ↗

Regulatory interactions between the Reg1-Glc7 protein phosphatase and the Snf1 protein kinase.Semantic proximity Read ↗

Functional analysis of the yeast Glc7-binding protein Reg1 identifies a protein phosphatase type 1-binding motif as essential for repression of ADH2 expression.Semantic proximity Read ↗

The GLC7 type 1 protein phosphatase is required for glucose repression in Saccharomyces cerevisiae.Semantic proximity Read ↗

Glucose-regulated interaction of a regulatory subunit of protein phosphatase 1 with the Snf1 protein kinase in Saccharomyces cerevisiae.Semantic proximity Read ↗

Genetic interactions between GLC7, PPZ1 and PPZ2 in saccharomyces cerevisiae.Semantic proximity Read ↗

PP1 phosphatase-binding motif in Reg1 protein of Saccharomyces cerevisiae is required for interaction with both the PP1 phosphatase Glc7 and the Snf1 protein kinase.Semantic proximity Read ↗

Glc8 is a glucose-repressible activator of Glc7 protein phosphatase-1.Semantic proximity Read ↗

The mutant type 1 protein phosphatase encoded by glc7-1 from Saccharomyces cerevisiae fails to interact productively with the GAC1-encoded regulatory subunit.Semantic proximity Read ↗

The type 1 phosphatase Reg1p-Glc7p is required for the glucose-induced degradation of fructose-1,6-bisphosphatase in the vacuole.Semantic proximity Read ↗

Sds22p is a subunit of a stable isolatable form of protein phosphatase 1 (Glc7p) from Saccharomyces cerevisiae.Semantic proximity Read ↗

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