Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Testicular Germ Cell-Associated Serine-Threonine Kinase, MAK, Is Dispensable for Sperm Formation

1 May 2002

Abstract excerpt

A member of the mitogen-activated protein kinase superfamily, MAK, has been proposed to have an important role in spermatogenesis, since Mak gene expression is highly restricted to testicular germ cells. To assess the biological function of MAK, we have established MAK-deficient (Mak(-/-)) mice. Mak(-/-) mice developed normally, and no gross abnormalities were observed. Spermatogenesis of the Mak(-/-) mice was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Reproductive Biology and Fertility
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11971961
DOI: 10.1128/mcb.22.10.3276-3280.2002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Testicular Germ Cell-Associated Serine-Threonine Kinase, MAK, Is Dispensable for Sperm FormationPMID 11971961Read ↗

MAPKs signaling is obligatory for male reproductive function in a development-specific mannerSemantic proximity Read ↗

Pyruvate kinase M in germ cells is essential for sperm motility and male fertility but not spermatogenesisSemantic proximity Read ↗

Testis‐specific serine kinase 3 is required for sperm morphogenesis and male fertilitySemantic proximity Read ↗

Expression and localization of five members of the testis-specific serine kinase (Tssk) family in mouse and human sperm and testisSemantic proximity Read ↗

Role of c-kit in mammalian spermatogenesisSemantic proximity Read ↗

Impaired Spermatogenesis and Fertility in Mice Carrying a Mutation in the Spink2 Gene Expressed Predominantly in TestesSemantic proximity Read ↗

Aurora A Kinase (AURKA) is required for male germline maintenance and regulates sperm motility in the mouse.Semantic proximity Read ↗

Germ cell-specific disruption of the Meig1 gene causes impaired spermiogenesis in mice.Semantic proximity Read ↗

Eef2k is not required for fertility in male miceSemantic proximity Read ↗

Knockout of Murine Mamld1 Impairs Testicular Growth and Daily Sperm Production but Permits Normal Postnatal Androgen Production and Fertility.Semantic proximity Read ↗

Targeting of a Germ Cell-specific Type 1 Hexokinase Lacking a Porin-binding Domain to the Mitochondria as Well as to the Head and Fibrous Sheath of Murine SpermatozoaSemantic proximity Read ↗

The acrosomal protein Dickkopf-like 1 (DKKL1) is not essential for fertility.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.