Article
Characterization of a direct oxygen sensor heme protein from Escherichia coli. Effects of the heme redox states and mutations at the heme-binding site on catalysis and structure.
The Journal of biological chemistry - 28 Jun 2002
Sasakura Yukie, Hirata Satoshi, Sugiyama Shunpei, Suzuki Shingo, Taguchi Sue, Watanabe Miki, Matsui Toshitaka, Sagami Ikuko, Shimizu Toru
Abstract excerpt
A protein containing a heme-binding PAS (PAS is from the protein names in which imperfect repeat sequences were first recognized: PER, ARNT, and SIM) domain from Escherichia coli has been implied a direct oxygen sensor (Ec DOS) enzyme. In the present study, we isolated cDNA for the Ec DOS full-length protein, expressed it in E. coli, and examined its structure-function relationships for the first time. Ec DOS was...
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