Article
Redox regulation of Fcgamma receptor-mediated phagocytosis: implications for host defense and tissue injury.
Antioxidants & redox signaling - 1 Feb 2002
Pricop Luminita, Salmon Jane E
Abstract excerpt
Recent advances in our understanding of the mechanisms that regulate acute and chronic inflammatory responses have revealed a key role for reactive oxygen intermediates in modulating the activation of neutrophils. Opsonized microbes and immune complexes initiate the oxidative burst by the engagement of receptors for immunoglobulin G, termed Fcgamma receptors. The regulation of phagocytic cell function by...
Topics
- Alleles
- Humans
- Models, Biological
- Oxidation-Reduction
- Phagocytosis
- Phosphorylation
- Receptors, IgG
- Respiratory Burst
- Signal Transduction
- Time Factors
