Article
The activity of leukocyte NADPH oxidase: regulation by p47PHOX cysteine and serine residues.
Antioxidants & redox signaling - 1 Feb 2002
Babior Bernard M
Abstract excerpt
The leukocyte NADPH oxidase is regulated chiefly by phosphorylation of the serines of p47(PHOX), one of its cytosolic subunits. Its activity is also regulated, however, by the four cysteines of the same subunit, as indicated by the replacement of those cysteines by alanines.
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