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Article

Novel insulin sensitizers: pharmacogenomic aspects.

Pharmacogenomics - 1 Jan 2002

Otto Carsten, Lehrke Michael, Göke Burkhard

Abstract excerpt

Thiazolidinediones (TZD, glitazones) are a new class of oral antidiabetic drugs which exert their insulin sensitizing action by stimulation of the nuclear transcription factor peroxisome proliferator-activated receptor gamma (PPAR-gamma). At present pioglitazone and rosiglitazone are available for clinical use. Different activation levels of PPAR-gamma and of co-factors determine the binding of PPAR-gamma to...

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Identifiers

PMID: 11966407
DOI: 10.1517/14622416.3.1.99

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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