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Article

RNA diversity has profound effects on the translation of neuronal nitric oxide synthase.

Proceedings of the National Academy of Sciences of the United States of America - 12 Oct 1999

Wang Y, Newton D C, Robb G B, Kau C L, Miller T L, Cheung A H, Hall A V, VanDamme S, Wilcox J N, Marsden P A

Abstract excerpt

A comprehensive analysis of the structure of neuronal nitric oxide synthase (nNOS; EC 1.14.13.39) mRNA species revealed NOS1 to be the most structurally diverse human gene described to date in terms of promoter usage. Nine unique exon 1 variants are variously used for transcript initiation in diverse tissues, and each is expressed from a unique 5'-flanking region. The dependence on unique genomic regions to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 10518591
DOI: 10.1073/pnas.96.21.12150
PMCID: PMC18427

Genes

NOS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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