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Article

Caenorhabditis elegans PlexinA, PLX-1, interacts with transmembrane semaphorins and regulates epidermal morphogenesis.

Development (Cambridge, England) - 1 May 2002

Fujii Takashi, Nakao Fumi, Shibata Yukimasa, Shioi Go, Kodama Eiji, Fujisawa Hajime, Takagi Shin

Abstract excerpt

The plexin family transmembrane proteins are putative receptors for semaphorins, which are implicated in the morphogenesis of animal embryos, including axonal guidance. We have generated and characterized putative null mutants of the C. elegans plexinA gene, plx-1. plx-1 mutants exhibited morphological defects: displacement of ray 1 and discontinuous alae. The epidermal precursors for the affected organs were...

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PMID: 11959816
DOI: 10.1242/dev.129.9.2053

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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