Article
Metabolite profiling of Phycomyces blakesleeanus carotene mutants reveals global changes across intermediary metabolism.
Microbiology (Reading, England) - 1 Nov 2016
Alcalde Eugenio, Fraser Paul David
Abstract excerpt
The filamentous fungus Phycomyces blakesleeanus provides a renewable biosource of industrial high-value compounds such as carotenes, other isoprenoids (ubiquinone and sterols), organic acids and fatty acids. Several Phycomyces mutants involved in the formation of β-carotene are available. For example, the carA mutants have a leaky mutation in the phytoene synthase and produce significantly lower amounts of...
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