Article
[Complement and serum immunoglobulins in homozygous and heterozygous sickle cell anemia in Senegal].
Dakar medical - 1 Jan 1999
Dieye T N, Ndiaye O, Ndiaye A B, Thiam D, Fall-Seck K, Diop S, Diop B M, Fall M, Diakhaté L
Abstract excerpt
Sickle cell disease is an hereditary hemoglobinopathy syndrome which provokes deglobulization crisis and infectious complications. These infectious diseases may be due to a permanent activation of the immune system. The aim of our study was to explore alternative pathway by measuring C3 complement and the classical pathway by C4 complement. The level of immunoglobulins IgA, IgG and IgM was also measured in the...
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