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Article

High risk for hyperlipidemia and the metabolic syndrome after an episode of hypertriglyceridemia during 13-cis retinoic acid therapy for acne: a pharmacogenetic study.

Annals of internal medicine - 16 Apr 2002

Rodondi Nicolas, Darioli Roger, Ramelet Albert-Adrien, Hohl Daniel, Lenain Vincent, Perdrix Jean, Wietlisbach Vincent, Riesen Walter F, Walther Thomas, Medinger Laurent, Nicod Pascal, Desvergne Béatrice, Mooser Vincent

Abstract excerpt

BACKGROUND: Administration of 13-cis retinoic acid (isotretinoin) for acne is occasionally accompanied by hyperlipidemia. It is not known why some persons develop this side effect. OBJECTIVE: To determine whether isotretinoin triggers a familial susceptibility to hyperlipidemia and the metabolic syndrome. DESIGN: Cross-sectional comparison. SETTING: University hospital in Lausanne, Switzerland. PARTICIPANTS: 102...

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Identifiers

PMID: 11955026
DOI: 10.7326/0003-4819-136-8-200204160-00007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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