Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Activation of the Interferon- <i>β</i> Promoter During Hepatitis C Virus RNA Replication

1 Mar 2002

Abstract excerpt

In this study we examined the impact of hepatitis C virus (HCV) RNA replication on the innate antiviral response of the host cell. Replication of an HCV subgenomic replicon stimulated the activation of the interferon (IFN)-beta promoter and the production of IFN in human hepatoma cells. Using a variety of functional assays, we found that HCV RNA replication induced the activation and DNA-binding activity of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hepatitis C virus research
Share to interferon and immune responses
Share to Systemic Lupus Erythematosus Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11952144
DOI: 10.1089/088282402317340215

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Activation of the Interferon- <i>β</i> Promoter During Hepatitis C Virus RNA ReplicationPMID 11952144Read ↗

Dynamic expression profiling of type I and type III interferon-stimulated hepatocytes reveals a stable hierarchy of gene expressionSemantic proximity Read ↗

Regulation of PKR and IRF-1 during hepatitis C virus RNA replicationSemantic proximity Read ↗

Hepatitis C Virus Infection Induces the Beta Interferon Signaling Pathway in Immortalized Human HepatocytesSemantic proximity Read ↗

Direct, Interferon-Independent Activation of the CXCL10 Promoter by NF-κB and Interferon Regulatory Factor 3 during Hepatitis C Virus InfectionSemantic proximity Read ↗

Innate Cellular Response to Virus Particle Entry Requires IRF3 but Not Virus ReplicationSemantic proximity Read ↗

A human and rhesus macaque interferon-stimulated gene screen reveals <i>ARHGEF3/XPLN</i> as an antiviral gene against hepatitis C virus and other flavivirusesSemantic proximity Read ↗

Initial HCV infection of adult hepatocytes triggers a temporally structured transcriptional program containing diverse pro- and anti-viral elementsSemantic proximity Read ↗

Transmitted/founder hepatitis C viruses induce cell-type- and genotype-specific differences in innate signaling within the liver.Semantic proximity Read ↗

Ribavirin Regulates Hepatitis C Virus Replication Through Enhancing Interferon-Stimulated Genes and Interleukin 8Semantic proximity Read ↗

Hepatitis C Virus Infection Impairs IRF-7 Translocation and Alpha Interferon Synthesis in Immortalized Human HepatocytesSemantic proximity Read ↗

Control of antiviral defenses through hepatitis C virus disruption of retinoic acid-inducible gene-I signalingSemantic proximity Read ↗

Expression of Interferon Lambda 4 Is Associated with Reduced Proliferation and Increased Cell Death in Human Hepatic CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.