Article
Alignment of myoblasts on ultrafine gratings inhibits fusion in vitro.
The international journal of biochemistry & cell biology - 1 Jul 2002
Clark P, Dunn G A, Knibbs A, Peckham M
Abstract excerpt
During development, skeletal muscle precursor cells fuse to form multi-nucleated myotubes. However, it is unclear how this fusion is regulated such that linear myotubes are produced. In a previous study, we found that linear arrays of myoblasts cultured on micropatterns of laminin fused to form linear myotubes of a constant diameter, independent of the width of the laminin track. This suggested that a mechanism...
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