Article
PC12 cell aggregation and neurite growth in gels of collagen, laminin and fibronectin.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience - 1 Jun 1996
Baldwin S P, Krewson C E, Saltzman W M
Abstract excerpt
PC12 cells form aggregates when suspended within three-dimensional, self-assembled, type I collagen gels; these aggregates increase in size over time. In addition, when the cells are cultured in the presence of nerve growth factor, they express neurites, which extend through the three-dimensional...
Topics
- Animals
- Cell Aggregation
- Collagen
- Culture Media
- DNA
- Extracellular Matrix
- Fibronectins
- Gels
- Image Processing, Computer-Assisted
- Laminin
- Microscopy, Electron, Scanning
- Microscopy, Fluorescence
- Nerve Growth Factors
- Nerve Regeneration
- Neurites
- PC12 Cells
- Phenotype
- Rats
