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Article

Relation of the -514C/T polymorphism in the hepatic lipase gene to serum HDL and LDL cholesterol levels in postmenopausal women under hormone replacement therapy.

Atherosclerosis - 1 May 2002

Yamakawa-Kobayashi Kimiko, Somekawa Yoshiaki, Fujimura Mitsuko, Tomura Shigeo, Arinami Tadao, Hamaguchi Hideo

Abstract excerpt

Hepatic lipase (HL) is a lipolytic enzyme that catalyzes hydrolysis of triglycerides and phospholipids in all major classes of lipoproteins. Recently, a -514C/T polymorphism in the promoter region of the HL gene was found to be associated with variations in hepatic lipase activity and serum high...

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Source

Identifiers

PMID: 11947893
DOI: 10.1016/s0021-9150(01)00675-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11947893-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Relation of the -514C/T polymorphism in the hepatic lipase gene to serum HDL and LDL cholesterol levels in postmenopausal women under hormone replacement therapy.PMID 11947893Read ↗

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Positive association of the hepatic lipase gene polymorphism c.514C > T with estrogen replacement therapy response.Semantic proximity Read ↗

The -514 C->T hepatic lipase promoter region polymorphism and plasma lipids: a meta-analysis.Semantic proximity Read ↗

C-514T polymorphism in hepatic lipase gene promoter is associated with elevated triglyceride levels and decreasing insulin sensitivity in nondiabetic Japanese subjects.Semantic proximity Read ↗

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Effects of hepatic lipase gene promoter nucleotide variations on serum HDL cholesterol concentration in the general Japanese population.Semantic proximity Read ↗

Hepatic lipase C-480T genotype-dependent benefit from long-term hormone replacement therapy for atherosclerosis progression in postmenopausal women.Semantic proximity Read ↗

Hepatic lipase C514T polymorphism and its relationship with plasma HDL-C levels and coronary artery disease in Koreans.Semantic proximity Read ↗

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