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Article

A short mutational hot spot in the first intron of BCL-6 is associated with increased BCL-6 expression and with longer overall survival in large B-cell lymphomas.

The American journal of pathology - 1 Apr 2002

Artiga María-Jesús, Sáez Ana-Isabel, Romero Cristina, Sánchez-Beato Margarita, Mateo Mari-Sol, Navas Concepción, Mollejo Manuela, Piris Miguel A

Abstract excerpt

BCL-6 somatic mutations have been described in normal and tumoral B lymphocytes, associated with germinal center transit. We analyzed mutations in the major mutation cluster of BCL-6 in a series of 45 large B-cell lymphomas (LBCLs) and 15 Burkitt's lymphomas, and their relation to the level of BC...

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Identifiers

PMID: 11943722
DOI: 10.1016/S0002-9440(10)62564-3
PMCID: PMC1867208

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11943722-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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