Article
Clinical expression and insulin sensitivity in type 2 diabetic patients with heterozygous mutations for haemochromatosis.
Diabetes & metabolism - 1 Feb 2002
Van Lerberghe S, Hermans M P, Dahan K, Buysschaert M
Abstract excerpt
BACKGROUND: Elevated iron metabolism indices as well as liver enzymes abnormalities have been reported in type 2 diabetic patients. The aim of this study was to determine the clinical and biological characteristics of overweight or obese type 2 diabetic subjects, with and without heterozygosity for HFE gene mutation (C282Y or H63D). We also assessed their insulin sensitivity and B cell function. METHODS: 90...
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