Article
Typical type 2 diabetes mellitus and HFE gene mutations: a population-based case - control study.
Human molecular genetics - 15 Jun 2003
Halsall David J, McFarlane Ian, Luan Jian'an, Cox Timothy M, Wareham Nicholas J
Abstract excerpt
Diabetes mellitus is a recognized consequence of hereditary haemochromatosis. Whether the common HFE mutations, that associate with this condition and pre-dispose to increases in serum iron indices, are over-represented in diabetic populations remains controversial. We present data from the largest case-control study of the C282Y and H63D HFE allele frequencies in typical type 2 diabetes mellitus, as defined by...
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