Article
Relaxation of imprinted expression of ZAC and HYMAI in a patient with transient neonatal diabetes mellitus.
Human genetics - 1 Feb 2002
Mackay D J G, Coupe A-M, Shield J P H, Storr J N P, Temple I K, Robinson D O
Abstract excerpt
Transient neonatal diabetes mellitus (TNDM) is a rare disease believed to result from overexpression of a paternally expressed gene controlled by a differentially methylated CpG island on chromosome 6q24. Two genes partially overlap the island: the cell-cycle-control gene ZAC and the untranslated gene HYMAI, the function of which is currently unknown. Proof that either gene is involved in TNDM would require...
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