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Article

DNA hypomethylation, transient neonatal diabetes, and prune belly sequence in one of two identical twins.

European journal of pediatrics - 1 Feb 2010

Laborie Lene Bjerke, Mackay Deborah J G, Temple I Karen, Molven Anders, Søvik Oddmund, Njølstad Pål Rasmus

Abstract excerpt

One known genetic mechanism for transient neonatal diabetes is loss of methylation at 6q24. The etiology of prune belly sequence is unknown but a genetic defect, affecting the mesoderm from which the triad abdominal muscle hypoplasia, urinary tract abnormalities, and cryptorchidism develop, has been suggested. We investigated a family, including one twin, with transient neonatal diabetes and prune belly sequence....

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Share to Chromosomes, Human, Pair 6
Share to Diabetes Mellitus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diseases in Twins

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Share to Infant, Newborn

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Source

Identifiers

PMID: 19521719
DOI: 10.1007/s00431-009-1008-y

Genes

ABCC8
DIRAS3
GCK
KCNJ11
PAX4
ZFP57
ZIC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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