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Article

Transient neonatal diabetes, ZFP57, and hypomethylation of multiple imprinted loci: a detailed follow-up.

Diabetes care - 1 Mar 2013

Boonen Susanne E, Mackay Deborah J G, Hahnemann Johanne M D, Docherty Louise, Grønskov Karen, Lehmann Anna, Larsen Lise G, Haemers Andreas P, Kockaerts Yves, Dooms Lutgarde, Vu Dung Chí, Ngoc C T Bich, Nguyen Phuong Bich, Kordonouri Olga, Sundberg Frida, Dayanikli Pinar, Puthi Vijith, Acerini Carlo, Massoud Ahmed F, Tümer Zeynep, Temple I Karen

Abstract excerpt

OBJECTIVE: Transient neonatal diabetes mellitus 1 (TNDM1) is the most common cause of diabetes presenting at birth. Approximately 5% of the cases are due to recessive ZFP57 mutations, causing hypomethylation at the TNDM locus and other imprinted loci (HIL). This has consequences for patient care...

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Share to Diabetes Mellitus, Type 1
Share to DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genomic Imprinting

Share to Genotype

Share to Infant, Newborn

Share to Infant, Newborn, Diseases

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Source

Open in PubMed Open full text

Identifiers

PMID: 23150280
DOI: 10.2337/dc12-0700
PMCID: PMC3579357

Genes

ZFP57

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23150280-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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