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Article

Characterization of the mouse aortic carboxypeptidase-like protein promoter reveals activity in differentiated and dedifferentiated vascular smooth muscle cells.

Circulation research - 5 Apr 2002

Layne Matthew D, Yet Shaw-Fang, Maemura Koji, Hsieh Chung-Ming, Liu Xiaoli, Ith Bonna, Lee Mu-En, Perrella Mark A

Abstract excerpt

The dedifferentiation and proliferation of vascular smooth muscle cells (VSMCs) contribute to the formation of vascular lesions. In this study, the regulation of aortic carboxypeptidase-like protein (ACLP) expression in VSMCs was investigated. After mouse carotid injury, the expression of ACLP increases in the dedifferentiated VSMCs of the neointima in a pattern that differs from that of smooth muscle...

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PMID: 11934842
DOI: 10.1161/01.res.0000013289.97650.c8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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