Article

Diagnosis of Invasive Mold Infection by Real-Time Quantitative PCR

2003-01-01

Abstract excerpt

We report the design and evaluation of a quantitative real-time polymerase chain reaction (PCR) assay to diagnose invasive mold infection (IMI) by detecting mold DNA in the serum. This assay detected 200 fg to 20 ng (5-log range) mold DNA and permitted a cutoff of 110 fg (3 genomes). Human or candidal DNA was not amplified. Specificity also was demonstrated by negative results in all 35 patients (76 serum samples)...

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Literature Corpus work: 5ca64ba2-f898-57b2-9ddd-6fe488f58bc6
DOI: 10.1309/rq05pp9neg6dadxr

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