Article
Sialylation is essential for early development in mice.
Proceedings of the National Academy of Sciences of the United States of America - 16 Apr 2002
Schwarzkopf Martina, Knobeloch Klaus-Peter, Rohde Elvira, Hinderlich Stephan, Wiechens Nicola, Lucka Lothar, Horak Ivan, Reutter Werner, Horstkorte Rüdiger
Abstract excerpt
Sialic acids are widely expressed as terminal carbohydrates on glycoconjugates of eukaryotic cells. Sialylation is crucial for a variety of cellular functions, such as cell adhesion or signal recognition, and regulates the biological stability of glycoproteins. The key enzyme of sialic acid biosy...
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