Article
Longitudinal changes in brain magnetic resonance imaging findings in children with sickle cell disease.
Blood - 15 Apr 2002
Pegelow Charles H, Macklin Eric A, Moser Franklin G, Wang Winfred C, Bello Jacqueline A, Miller Scott T, Vichinsky Elliott P, DeBaun Michael R, Guarini Ludovico, Zimmerman Robert A, Younkin Donald P, Gallagher Dianne M, Kinney Thomas R
Abstract excerpt
Children with sickle cell anemia (HbSS) are at high risk for neurologically overt cerebral infarcts associated with stroke and neurologically silent cerebral infarcts correlated with neuropsychometric deficit. We used complete magnetic resonance imaging (MRI) histories from 266 HbSS children, aged 6 through 19 years, who were enrolled in the Cooperative Study of Sickle Cell Disease (CSSCD) to examine silent...
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