Article
Pediatric sickle cell disease: past successes and future challenges.
Pediatric research - 1 Jan 2017
Meier Emily Riehm, Rampersad Angeli
Abstract excerpt
Once a fatal disease of childhood, more than 95% of patients born today with sickle cell disease (SCD) in developed countries are expected to survive into adulthood, largely because of improvements in supportive and preventive care (newborn screening, penicillin prophylaxis, transcranial Doppler (TCD) screening). Hydroxyurea (HU) therapy, the only oral medication currently available to prevent SCD complications,...
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