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Article

Does the medication pattern reflect the CYP2D6 genotype in patients with diagnoses within the schizophrenic spectrum?

Journal of clinical psychopharmacology - 1 Feb 2012

Jürgens Gesche, Rasmussen Henrik B, Werge Thomas, Dalhoff Kim, Nordentoft Merete, Andersen Stig E

Abstract excerpt

BACKGROUND: Cytochrome P450 2D6 enzyme (CYP2D6) is an important metabolic pathway for many antipsychotics. Its genetic polymorphism causes pharmacokinetic variability that might lead to adverse drug reactions or treatment failure unless countered by appropriate dose adjustments or shift to CYP2D6-independent antipsychotics. PURPOSE: To investigate the clinical impact of CYP2D6 genotype in patients with a...

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Source

Identifiers

PMID: 22198443
DOI: 10.1097/JCP.0b013e31823f6b6a

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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