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A human homologue of mouse Mater, a maternal effect gene essential for early embryonic development

1 Apr 2002

Abstract excerpt

BACKGROUND: Mater is a maternal effect gene required for early embryonic development in mice, and its protein serves as an autoantigen in a mouse model of autoimmune premature ovarian failure. METHODS: Human MATER cDNA was cloned by PCR techniques. The mRNA and protein were determined using hybridization and immunodetection respectively. The cDNA and protein sequences were analysed using bioinformatics software....

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PMID: 11925379
DOI: 10.1093/humrep/17.4.903

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