From cytogenetics to next-generation sequencing technologies: advances in the detection of genome rearrangements in tumors.

Abstract excerpt

Genome rearrangements have long been recognized as hallmarks of human tumors and have been used to diagnose cancer. Techniques used to detect genome rearrangements have evolved from microscopic examinations of chromosomes to the more recent microarray-based approaches. The availability of next-generation sequencing technologies may provide a means for scrutinizing entire cancer genomes and transcriptomes at...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cytogenetics
• Share to Gene Rearrangement