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Article

Environmental modulation of atherosclerosis end points in familial hypercholesterolemia.

Atherosclerosis. Supplements - 1 Mar 2002

Hegele Robert A

Abstract excerpt

In familial hypercholesterolemia (FH), early coronary heart disease (CHD) is a complex trait that results from a large monogenic component of susceptibility due to elevated LDL cholesterol. This was demonstrated by observation of the high risk of early CHD in FH subjects compared with the general population. However, not all subjects with a LDLR gene mutation suffer with early CHD. Furthermore, studies in...

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Identifiers

PMID: 11923122
DOI: 10.1016/s1567-5688(01)00013-7

Genes

LDLR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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