Genetic and environmental factors affecting the incidence of coronary artery disease in heterozygous familial hypercholesterolemia.

doi:10.1161/01.atv.11.2.290

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Article

Genetic and environmental factors affecting the incidence of coronary artery disease in heterozygous familial hypercholesterolemia.

Arteriosclerosis and thrombosis : a journal of vascular biology - 1 Jan 2000

Hill J S, Hayden M R, Frohlich J, Pritchard P H

Abstract excerpt

This study explores the influence of selected genetic and environmental factors on the clinical expression of heterozygous familial hypercholesterolemia (FH). A detailed examination of the physical and biochemical features of FH was performed in a large cohort of 208 females and 156 males. Females with FH had higher levels of total, low density lipoprotein (LDL), and high density lipoprotein (HDL) cholesterol...

Topics

Adult
Apolipoproteins E
Cholesterol, HDL
Coronary Disease
Female
Humans
Hyperlipoproteinemia Type II
Incidence
Lipoproteins, LDL
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Polymorphism, Genetic

Risk Factors

Sex Factors

Smoking

Triglycerides

Source

Open in PubMed

Identifiers

PMID: 1998646
DOI: 10.1161/01.atv.11.2.290

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1998646-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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