Article
20 S proteasomes are imported as precursor complexes into the nucleus of yeast.
Journal of molecular biology - 29 Mar 2002
Lehmann Andrea, Janek Katharina, Braun Beate, Kloetzel Peter-Michael, Enenkel Cordula
Abstract excerpt
The mechanism by which yeast 20 S proteasomes are imported into the nucleus is still unresolved. Here, we provide the first evidence that 20 S proteasomes are imported as precursor complexes into the nucleus. By using the srp1-49 mutant which is deficient in nuclear import of cargos with classica...
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