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Article

Genetic regulation of ionizing radiation sensitivity and breast cancer risk.

Environmental and molecular mutagenesis - 1 Jan 2002

Hu Jennifer J, Smith Tasha R, Miller Mark Steven, Lohman Kurt, Case L Douglas

Abstract excerpt

Genetic variability in DNA repair may contribute to hypersensitivity to ionizing radiation (IR) and susceptibility to breast cancer. We used samples collected from a clinic-based breast cancer case-control study to test the working hypothesis that amino acid substitution variants of DNA repair genes may contribute to prolonged cell-cycle delay following IR and breast cancer risk. Fluorescence-activated cell...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11921191
DOI: 10.1002/em.10058

Genes

XRCC1
XRCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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