Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Neuroradiologic correlates of clinical disability and progression in the X-linked leukodystrophy Pelizaeus-Merzbacher disease.

Journal of the neurological sciences - 15 Dec 2013

Laukka Jeremy J, Stanley Jeffrey A, Garbern James Y, Trepanier Angela, Hobson Grace, Lafleur Tori, Gow Alexander, Kamholz John

Abstract excerpt

OBJECTIVE: To determine whether quantitative measure of magnetic resonance imaging data from patients with the inherited leukodystrophy, Pelizaeus-Merzbacher disease (PMD) correlates with clinical severity or progression. METHODS: In our current work we have analyzed the clinical phenotypes and MRI scans of 51 male patients with PMD and 10 female carriers for whom the PLP1 genotype had been determined. In...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain
Share to Corpus Callosum

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Image Processing, Computer-Assisted

Share to Myelin Proteolipid Protein

Share to Nerve Fibers, Myelinated

Share to Nervous System Diseases

Share to Pelizaeus-Merzbacher Disease

Share to Persons with Disabilities

Source

Open in PubMed Open full text

Identifiers

PMID: 24139698
DOI: 10.1016/j.jns.2013.08.030
PMCID: PMC3969727

Genes

PLP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neuroradiologic correlates of clinical disability and progression in the X-linked leukodystrophy Pelizaeus-Merzbacher disease.PMID 24139698Read ↗

The magnetic resonance imaging spectrum of Pelizaeus-Merzbacher disease: A multicenter study of 19 patients.Semantic proximity Read ↗

Normative modeling for quantitative brain MRI phenotyping and biomarker discovery for pediatric leukodystrophiesSemantic proximity Read ↗

Identification of PMD subgroups using a myelination score for PMD.Semantic proximity Read ↗

Leukodystrophy Imaging: Insights for Diagnostic DilemmasSemantic proximity Read ↗

Neurogenetics of Pelizaeus-Merzbacher disease.Semantic proximity Read ↗

Update on Leukodystrophies: A Historical Perspective and Adapted DefinitionSemantic proximity Read ↗

Pelizaeus-Merzbacher disease, Pelizaeus-Merzbacher-like disease 1, and related hypomyelinating disorders.Semantic proximity Read ↗

Degree of Hypomyelination and Magnetic Resonance Spectroscopy Findings in Patients with Pelizaeus Merzbacher PhenotypeSemantic proximity Read ↗

Pelizaeus-Merzbacher disease in patients with molecularly confirmed diagnosis.Semantic proximity Read ↗

Neuropathology and genetics of Pelizaeus-Merzbacher disease.Semantic proximity Read ↗

Pelizaeus-Merzbacher Disease: A Caregiver Assessment of Disease Impact.Semantic proximity Read ↗

The molecular and cellular defects underlying Pelizaeus-Merzbacher disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.