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Article

Five men with arresting and relapsing cerebral adrenoleukodystrophy.

Journal of neurology - 1 Mar 2021

Carlson Aaron M, Huffnagel Irene C, Verrips Aad, van der Knaap Marjo S, Engelen Marc, Van Haren Keith

Abstract excerpt

BACKGROUND: X-linked adrenoleukodystrophy (ALD) is the most common genetic peroxisomal disorder with an estimated prevalence of 1:15,000. Approximately two-thirds of males with ALD manifest the inflammatory demyelinating cerebral phenotype (cALD) at some disease stage, in which focal, inflammatory lesions progress over months to years. Hematopoietic stem-cell transplantation can permanently halt cALD progression,...

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Identifiers

PMID: 32995952
DOI: 10.1007/s00415-020-10225-7
PMCID: PMC8025682

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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