Article
Comparison of phenotypic and genotypic methods for the detection of clarithromycin resistance in Mycobacterium avium.
The Journal of antimicrobial chemotherapy - 1 Apr 2002
Thiermann Sacha, Munzinger Jürg, Bodmer Thomas
Abstract excerpt
The MICs of clarithromycin for 10 clinical isolates of Mycobacterium avium were determined using three methods: Bactec 460-TB, broth microdilution and Etest. The results were compared with the presence of resistance mutations in the 23S rRNA gene. Isolates were obtained from five AIDS patients who were treated with clarithromycin. Five isolates were recovered before and five during treatment. MICs were...
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