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Article

Detection and quantification of multiple drug resistance mutations in HIV-1 reverse transcriptase by an oligonucleotide ligation assay.

Journal of human virology - 1 Jan 2000

Villahermosa M L, Beck I, Pérez-Alvarez L, Contreras G, Frenkel L M, Osmanov S, de Parga E V, Delgado E, Manjon N, Cuevas M T, Thomson M M, Medrano L, Najera R

Abstract excerpt

OBJECTIVES: To develop an assay for the early detection and quantification of minor human immunodeficiency virus-1 populations bearing multiple drug resistance (MDR) mutations. STUDY DESIGN/METHODS: The oligonucleotide ligation assay (OLA) is based on ligation of probe and detector oligonucleotid...

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Source

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PMID: 11907381

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11907381-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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