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Article

Glycosylation and epitope mapping of the 5T4 glycoprotein oncofoetal antigen.

The Biochemical journal - 1 Apr 2002

Shaw David M, Woods Andrew M, Myers Kevin A, Westwater Caroline, Rahi-Saund Veena, Davies Michael J, Renouf David V, Hounsell Elizabeth F, Stern Peter L

Abstract excerpt

The human 5T4 oncofoetal antigen is a focus for development of several antibody-directed therapies on the basis of the murine monoclonal antibody against 5T4 (mAb5T4), which recognizes a conformational epitope. 5T4 molecules are highly N-glycosylated transmembrane glycoproteins whose extracellular domain contains two regions of leucine-rich repeats (LRRs) and associated flanking regions, separated by an...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 11903056
DOI: 10.1042/0264-6021:3630137
PMCID: PMC1222460

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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