Molecular organization of the genes required for the synthesis of type 1 capsular polysaccharide of <i>Streptococcus pneumoniae</i>: formation of binary encapsulated pneumococci and identification of cryptic dTDP‐rhamnose biosynthesis genes

Abstract excerpt

We report here the molecular organization of the capsular locus (cap1) of the type 1 pneumococcus. This locus is located between dexB and aliA and flanked by IS1167 insertion elements. Sequence analysis showed that the cluster contains 11 genes (cap1A to cap1K), which are apparently arranged as a single transcriptional unit. The presence of a functional promoter (cap1p) located upstream of cap1A has been...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Carbohydrate Chemistry and Synthesis
• Share to Pneumonia and Respiratory Infections