Article
Biochemical and genetic markers of iron status and the risk of coronary artery disease: an angiography-based study.
Clinical chemistry - 1 Jan 2002
Bozzini Claudia, Girelli Domenico, Tinazzi Elisa, Olivieri Oliviero, Stranieri Chiara, Bassi Antonella, Trabetti Elisabetta, Faccini Giovanni, Pignatti Pier Franco, Corrocher Roberto
Abstract excerpt
BACKGROUND: Iron may promote coronary atherosclerotic disease (CAD) by increasing lipid peroxidation. Studies on biochemical or genetic markers of body iron stores as risk factors for CAD have yielded conflicting results. METHODS: We studied 849 individuals with a clear-cut definition of the CAD phenotype, i.e., with (CAD; n = 546) or without (CAD-free; n = 303) angiographically documented disease. We determined...
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