Article
Antibodies targeting extractable nuclear antigens: historical development and current knowledge
1 Dec 2001
Abstract excerpt
The extractable nuclear antigens (ENA) are a heterogeneous group of ribonucleoproteins and non‐histone proteins with different functions in nuclear metabolism. The detection of antibodies targeting ENA is a well‐established tool in the diagnosis of autoimmune diseases such as lupus erythematosus (LE), progressive systemic sclerosis (PSS), polymyositis (PM), dermatomyositis (DM), mixed connective tissue disease...