Article
[Analysis of polymorphism of the number of tandem repeats in the aggrecan gene exon G3 in the families with idiopathic scoliosis].
Genetika - 1 Feb 2002
Zorkol'tseva I V, Liubinskiĭ O A, Sharipov R N, Zaĭdman A M, Aksenovich T I, Dymshits G M
Abstract excerpt
In our previous study we showed that the inheritance of pronounced forms of idiopathic scoliosis was described by an autosomal-dominant major gene model assuming incomplete sex- and age-dependent penetrance. In the present study a search for the major gene was carried out by means of testing candidate genes. The aggrecan gene with known polymorphism of the number of tandem repeats in exon G3 was considered to be...
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