Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pressure overload induces heterologous expression of the atrial natriuretic factor (ANF) gene.

IUBMB life - 1 Dec 2001

Dosch J C, Szwerc M F, Lin J C, Magovern J A, Edwards J G

Abstract excerpt

Several investigations have demonstrated the regional heterogeneity of myocardial phenotype, and hypertrophy may also induce regionally disparate changes. We have utilized the direct DNA injection technique to study regional variations in overload-induced ANF expression. Pressure overload was induced by stenosis of the ascending aorta in canines. ANF promoter reporters were injected into the left ventricle; in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Pressure
Share to Aortic Valve Stenosis
Share to Atrial Natriuretic Factor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Reporter

Share to Hypertrophy

Share to Luciferases

Share to Myocardium

Source

Identifiers

PMID: 11895081
DOI: 10.1080/152165401317291174

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pressure overload induces heterologous expression of the atrial natriuretic factor (ANF) gene.PMID 11895081Read ↗

Novel technique of aortic banding followed by gene transfer during hypertrophy and heart failureSemantic proximity Read ↗

Control of Cardiac Gene Expression by Mechanical StressSemantic proximity Read ↗

A transgenic mouse model for the simultaneous monitoring of ANF and BNP gene activity during heart development and diseaseSemantic proximity Read ↗

Regulation of cardiac gene expression during myocardial growth and hypertrophy: molecular studies of an adaptive physiologic responseSemantic proximity Read ↗

Atrial natriuretic peptide dose-dependently inhibits pressure overload-induced cardiac remodeling.Semantic proximity Read ↗

Angiotensin II type1a receptor gene expression in the heart: AP-1 and GATA-4 participate in the response to pressure overload.Semantic proximity Read ↗

Cardiac-specific attenuation of natriuretic peptide A receptor activity accentuates adverse cardiac remodeling and mortality in response to pressure overload.Semantic proximity Read ↗

Molecular regulation of the brain natriuretic peptide gene.Semantic proximity Read ↗

Altered expression of Na+ transporters at the mRNA level in rat normal and hypertrophic myocardium.Semantic proximity Read ↗

Mechanical Strain Increases Expression of the Brain Natriuretic Peptide Gene in Rat Cardiac MyocytesSemantic proximity Read ↗

Genetic variation in angiotensin-converting enzyme does not prevent development of cardiac hypertrophy or upregulation of angiotensin II in response to aortocaval fistula.Semantic proximity Read ↗

Targeted disruption of the gene for natriuretic peptide receptor-A worsens hypoxia-induced cardiac hypertrophySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.