Article
An integrated evaluation of endothelial constitutive nitric oxide synthase polymorphisms and coronary artery disease in men.
Clinical science (London, England : 1979) - 1 Sept 2004
Agema Willem R P, de Maat Moniek P M, Zwinderman Aeilko H, Kastelein John J P, Rabelink Ton J, van Boven Ad J, Feskens Edith J M, Boer Jolanda M A, van der Wall Ernst E, Jukema J Wouter
Abstract excerpt
In the present study, we sought to evaluate the role of three polymorphisms in the ecNOS (endothelial constitutive nitric oxide synthase) gene in relation to the existence, severity and progression of CAD (coronary artery disease), MI (myocardial infarction) and the occurrence of ischaemia in a predominantly Caucasian population. Patients with CAD (n = 760) and age- and sex-matched population-based controls (n =...
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